CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 171 enrolled
Drug / intervention
AZD9291drug
Likely dose
AZD9291 80 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02442349
NCT02442349Phase 2Completed

A Phase II, Open Label, Single-arm Study to Assess the Safety and Efficacy of AZD9291 in Asia Pacific Patients With Locally Advanced/Metastatic Non-Small Cell Lung Cancer Whose Disease Has Progressed With Previous Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Therapy and Whose Tumours Harbour a T790M Mutation Within the Epidermal Growth Factor Receptor Gene.

AstraZeneca·interventional·Posted May 13, 2015·Updated Jan 9, 2026

In Brief

A Phase 2 clinical trial evaluating AZD9291 for Non-Small Cell Lung Cancer. Completed, enrolled 171 participants across 30 sites in 3 countries.

Detailed Summary

A Phase II, Open Label, Single-arm Study to Assess the Safety and Efficacy of AZD9291 in Asia Pacific Patients with Locally Advanced/Metastatic Non-Small Cell Lung Cancer whose Disease has Progressed with Previous Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Therapy and whose Tumours harbour a T790M mutation within the Epidermal Growth Factor Receptor Gene

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, China, South Korea
Collaborators--

Timeline

Phase 2CompletedFinished
20162017201820192020202120222023202420252026
First PostedMay 13, 2015
Enrollment StartJun 22, 2015
Primary CompletionMar 4, 2016
Study CompletionNov 28, 2025
TodayJul 2, 2026
Enrollment to primary: 8 monthsPosted 11.1 years ago

Interventions

AZD9291drug

Once daily tablet 80 mg