CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 18 enrolled
Drug / intervention
CO2-Laser stimulation (Laser Stimulation Device, SIFEC)device
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02442726
NCT02442726N/ACompleted
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Activation of A-delta-fibres and C-fibres in a First Degree Thermal Injury in Volunteers

University of Copenhagen·interventional·Posted May 13, 2015·Updated Dec 3, 2015

In Brief

A clinical study evaluating CO2-Laser stimulation (Laser Stimulation Device, SIFEC) for Healthy Subjects. Completed, enrolled 18 participants across 1 site.

Detailed Summary

The aim of this study is to measure reaction times and thermal detection thresholds to CO2 laser stimulation of the skin, before and after a first degree thermal injury, in the primary and secondary hyperalgesia area, in order to investigate whether different nerve-fiber classes are activated in the post-injury phase. The study results are expected to uncover existence of a peripheral inflammatory input contributing to secondary hyperalgesia.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealthy Subjects
CountriesDenmark
Collaborators--

Timeline

N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedMay 13, 2015
Enrollment StartMay 1, 2015
Primary CompletionSep 1, 2015
Study CompletionNov 1, 2015
TodayJul 2, 2026
Enrollment to primary: 4 monthsPosted 11.1 years ago

Interventions

CO2-Laser stimulation (Laser Stimulation Device, SIFEC)device

Laser stimuli are evenly applied in 15 spots (each 6 mm in diameter) in the primary hyperalgesic zone (application zone of the contact thermode) and in the secondary hyperalgesic zone (1 cm outside the application zone of the contact thermode).