CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 254 enrolled
Drug / intervention
NGM282 +1 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02443116
NCT02443116Phase 2Completed

A Phase 2, Randomized, Double-blind, Placebo-controlled Study With Additional Open-label, Single-blind and Placebo-controlled Cohorts to Assess the Safety, Tolerability, and Efficacy of NGM282 in Patients With Nonalcoholic Steatohepatitis

NGM Biopharmaceuticals, Inc·interventional·Posted May 13, 2015·Updated Jul 23, 2025

In Brief

A Phase 2 clinical trial evaluating NGM282 and Placebo for Nonalcoholic Steatohepatitis (NASH). Completed, enrolled 254 participants across 22 sites in 3 countries.

Detailed Summary

The purpose of this study is to determine the safety, tolerability, and efficacy of NGM282 in patients with nonalcoholic steatohepatitis.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, Puerto Rico, United States

Timeline

Phase 2CompletedFinished
20162017201820192020202120222023202420252026
First PostedMay 13, 2015
Enrollment StartJul 31, 2015
Primary CompletionDec 6, 2019
Study CompletionJan 17, 2020
TodayJul 2, 2026
Enrollment to primary: 4.3 yearsPosted 11.1 years ago

Interventions

NGM282biological

Placeboother