CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 45 enrolled
Drug / intervention
Bimatoprost 0.01% +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02448043
NCT02448043N/ACompleted

Cutaneous Prostaglandin Application: Nail Growth, Nail Brittleness, and Eye Pressure

Northwestern University·interventional·Posted May 19, 2015·Updated Dec 13, 2019

In Brief

A clinical study evaluating Bimatoprost 0.01% and Placebo: saline for Nail Growth Cessation and Intraocular Pressure. Completed, enrolled 45 participants across 1 site.

Detailed Summary

Topical prostaglandin agents are used to help reduce eye pressure in glaucoma patients. Bimatoprost (Lumigan 0.01%) is such an agent (Allergan, Inc.). Several of our patients on bimatoprost and an observational study of patients on bimatoprost in another center reported that fingernails grew longer and became less brittle using the topical eye drops to the eyes. The purpose of the double-blinded study is to determine whether the application of the eye drops directly to the proximal nail fold of one hand using the opposite hand as a control will result in longer nails, less brittle nails, and reduced eye pressures should any of the medication be absorbed into the systemic circulation.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
CollaboratorsAllergan

Timeline

N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedMay 19, 2015
Enrollment StartJun 4, 2015
Primary CompletionMay 6, 2016
TodayJul 2, 2026
Enrollment to primary: 11 monthsPosted 11.1 years ago

Interventions

Bimatoprost 0.01%drug

Bimatoprost drops added to the proximal nail folds of the randomized study hand digits two times per day for 30 days

Placebo: salineother

Placebo drops added to the proximal nail folds of the hand digits opposite the study hand two times per day for 30 days