CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 36 enrolled
Drug / intervention
Tolcapone +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02448654
NCT02448654N/ACompleted
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COMT Inhibition as a Novel Treatment for Nicotine Addiction in Women

Yale University·interventional·Posted May 19, 2015·Updated Nov 24, 2020

In Brief

A clinical study evaluating Tolcapone and Sugar Pill for Nicotine Dependence. Completed, enrolled 36 participants across 1 site.

Detailed Summary

The purpose of this study is to use a medication tolcapone and or placebo to test if the symptoms of nicotine withdrawal lessens , and or changes in smoking urges, and mental reasoning in female smokers over a 72 hour period.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsNicotine Dependence
CountriesUnited States
CollaboratorsUS Department of Veterans Affairs, National Institute on Drug Abuse (NIDA)

Timeline

N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedMay 19, 2015
Enrollment StartOct 23, 2015
Primary CompletionJun 30, 2019
TodayJul 2, 2026
Enrollment to primary: 3.7 yearsPosted 11.1 years ago

Interventions

Tolcaponedrug

Tolcapone will be compared to sugar pill

Sugar Pilldrug

The sugar pill (placebo) will be compared to tolcapone