At a glance
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T-1000: Latent Structure of Multi-level Assessments and Predictors of Outcomes in Psychiatric Disorders
In Brief
An observational study evaluating standardized diagnostic assessment, self-report questionnaires, and 6 other interventions for Depression and 3 related conditions. Completed, enrolled 1,271 participants across 1 site.
Detailed Summary
In this study the investigators will seek to improve our understanding of how positive and negative valence systems, cognition, and arousal/interoception are inter-related in disorders of mood, substance use, and eating behavior. The investigators will recruit 1000 individuals and use a wide range of assessment tools, neuroimaging measures, blood and microbiome collections and behavioral tasks to complete the baseline and follow-up study visits. Upon completion, the investigators aim to have robust and reliable dimensional measures that quantify these systems and a set of assessments that should be recommended as a clinical tool to enhance outcome prediction for the clinician and assist in determining who will likely benefit from what type of intervention.