CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 275 enrolled
Drug / intervention
Linagliptin +5 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02453555
NCT02453555Phase 3Completed

A Phase III, Randomised, Double-blind, Parallel Group, 52 Week Study to Evaluate Efficacy and Safety of Once Daily Empagliflozin and Linagliptin Fixed Dose Combination Compared With Linagliptin Plus Placebo in Japanese Type 2 Diabetes Mellitus Patients With Insufficient Glycaemic Control After 16 Weeks Treatment With Once Daily Linagliptin 5 mg.

Boehringer Ingelheim·interventional·Posted May 25, 2015·Updated Feb 15, 2019

In Brief

A Phase 3 clinical trial evaluating Linagliptin, Empagliflozin placebo + linagliptin placebo low dose, and 4 other interventions for Diabetes Mellitus, Type 2. Completed, enrolled 275 participants across 40 sites.

Detailed Summary

This trial will compare the use of fixed dose combination of empagliflozin and linagliptin to linagliptin alone in patient with type 2 diabetes mellitus

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesJapan

Timeline

Phase 3CompletedFinished
20162017201820192020202120222023202420252026
First PostedMay 25, 2015
Enrollment StartMay 14, 2015
Primary CompletionAug 26, 2016
Study CompletionMar 27, 2017
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 11.1 years ago

Interventions

Linagliptindrug

Empagliflozin placebo + linagliptin placebo low dosedrug

Matching placebo empagliflozin + linagliptin

Empagliflozin + linagliptin low dosedrug

tablet

Linagliptin placebodrug

Matching placebo linagliptin

Empagliflozin + linagliptin high dosedrug

tablet

Empa + lina highdose placebodrug