CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 14 enrolled
Drug / intervention
Clean air +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02469428
NCT02469428N/ACompleted
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Epigenetic Effect Modifications With Ozone Exposure on Healthy Volunteers

Environmental Protection Agency (EPA)·interventional·Posted Jun 11, 2015·Updated Jul 30, 2019

In Brief

A clinical study evaluating Clean air and Ozone for Exposure to Environmental Pollution, Non-occupational. Completed, enrolled 14 participants across 1 site.

Detailed Summary

The purpose of this protocol is to assess whether epigenetic factors in healthy individuals make a person more or less responsive to lung inflammation following ozone exposures.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsExposure to Environmental Pollution, Non-occupational
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedJun 11, 2015
Enrollment StartDec 1, 2013
Primary CompletionJul 1, 2017
Study CompletionNov 5, 2018
TodayJul 2, 2026
Enrollment to primary: 3.6 yearsPosted 11.1 years ago

Interventions

Clean airother

Each subject will be exposed to clean air for 2 hours. Subjects will exercise on a bike. Each exercise session will consist of a 15 minute exercise interval at a level of up to 20 L/min/m2 BSA followed by a 15 minute rest period, repeated 4 times.

Ozoneother

Each subject will be exposed to 0.3 ppb ozone for 2 hours. Subjects will exercise on a bike. Each exercise session will consist of a 15 minute exercise interval at a level of up to 20 L/min/m2 BSA followed by a 15 minute rest period, repeated 4 times.