CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 176 enrolled
Drug / intervention
Carotid Endarterectomy or Stentingprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02476396
NCT02476396N/ACompleted
CompareCT.gov

Structural Stability of Carotid Plaque and Symptomatology

University of Wisconsin, Madison·observational·Posted Jun 19, 2015·Updated Aug 16, 2024

In Brief

An observational study evaluating Carotid Endarterectomy or Stenting for Carotid Stenosis and 5 related conditions. Completed, enrolled 176 participants across 1 site.

Detailed Summary

The purpose of the research is to understand structural plaque abnormalities that make a carotid plaque unstable and brake off (embolize) which would help to predict and treat individuals who are likely to suffer not only classic episodic major strokes but also cognitive impairment.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsCarotid Stenosis, Stroke, Carotid Artery Plaque, Transient Ischemic Attack, Cerebrovascular Accident, Carotid Artery Stenosis
CountriesUnited States
CollaboratorsNational Heart, Lung, and Blood Institute (NHLBI), National Institute of Neurological Disorders and Stroke (NINDS)

Timeline

N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedJun 19, 2015
Enrollment StartNov 9, 2015
Primary CompletionJul 14, 2024
TodayJul 2, 2026
Enrollment to primary: 8.7 yearsPosted 11.0 years ago

Interventions

Carotid Endarterectomy or Stentingprocedure

Carotid endarterectomy is a procedure to treat carotid artery disease. This disease occurs when fatty, waxy deposits build up in one of the carotid arteries. The carotid arteries are blood vessels located on each side of your neck (carotid arteries). This buildup of plaques (atherosclerosis) may restrict blood flow to your brain. Removing plaques causing the narrowing in the artery can improve blood flow in your carotid artery and reduce your risk of stroke. In carotid endarterectomy, you an anesthetic. Your surgeon makes an incision along the front of your neck, opens your carotid artery and removes the plaques that are clogging your artery. Your surgeon then repairs the artery with stitches or a patch made with a vein or artificial material (patch graft). Source: Mayo Clinic Carotid stenting uses a expandable metal coil to prevent the artery from narrowing.