CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 242 enrolled
Drug / intervention
Patient Controlled Epidural (PCEA) +1 moredrug
Likely dose
Patient Controlled Epidural (PCEA) 4mlfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02478372
NCT02478372N/ACompleted
CompareCT.gov

Patient Controlled Epidural Analgesia Versus Local Infiltration Analgesia Following Knee Arthroplasty Within an Enhanced Recovery Programme - a Randomised Controlled Trial

Golden Jubilee National Hospital·interventional·Posted Jun 23, 2015·Updated Nov 10, 2015

In Brief

A clinical study evaluating Patient Controlled Epidural (PCEA) and Local Infiltration Analgesia (LIA) for Osteoarthritis. Completed, enrolled 242 participants.

Detailed Summary

The purpose of this study was to determine if the method of peri-operative analgesia used following total Knee Replacement surgery affected the progress towards rehabilitation goals and to determine whether the analgesia had any impact on long term outcomes.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsOsteoarthritis
Countries--
CollaboratorsGlasgow Caledonian University

Timeline

N/ACompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedJun 23, 2015
Enrollment StartApr 1, 2010
Primary CompletionAug 1, 2011
Study CompletionNov 1, 2012
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 11.0 years ago

Interventions

Patient Controlled Epidural (PCEA)drug

Following the operation, 4ml of 0.25% levobupivacaine was administered and the catheter was connected to a PCEA. Self-medication with a bolus 2ml of 0.125% bupivacaine via the PCEA system with a lockout time of 15 minutes until the following morning (post-operative day one) when it was stopped.

Local Infiltration Analgesia (LIA)drug

Subcutaneous infiltration during surgery using 200ml of 0.2% plain ropivacaine.