At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Oral v. Injection Naltrexone in Hospital: Comparative Effectiveness for Alcoholism
In Brief
A Phase 4 clinical trial evaluating Oral naltrexone (PO-NTX) and Extended-release injectable naltrexone (XR-NTX) for Heavy Drinking and 2 related conditions. Completed, enrolled 248 participants across 1 site.
Detailed Summary
The specific aims of this pragmatic randomized controlled trial are to compare initiating injectable extended release naltrexone (XR-NTX) or oral naltrexone (PO-NTX) at the time of discharge from a medical hospitalization for patients with alcohol use disorder (AUD) on: 1) alcohol consumption and consequences, and 2) acute healthcare utilization (including hospital readmission and emergency visits) and cost-effectiveness. In exploratory analyses, the investigators will assess moderators of medication effects including demographic, behavioral, and genetic factors.
Study Details
Timeline
Interventions
oral naltrexone
injectable naltrexone