CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 7 enrolled
Drug / intervention
Lirilumab +1 moredrug
Likely dose
Lirilumab 3 mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02481297
NCT02481297Phase 2Completed

Lirilumab (Anti-KIR mAb) Combined With Rituximab for Relapsed, Refractory or High-risk Untreated Patients With Chronic Lymphocytic Leukemia (CLL)

M.D. Anderson Cancer Center·interventional·Posted Jun 25, 2015·Updated May 28, 2020

In Brief

A Phase 2 clinical trial evaluating Lirilumab and Rituximab for Leukemia and 2 related conditions. Completed, enrolled 7 participants across 1 site.

Detailed Summary

The goal of this clinical research study is to learn if lirilumab in combination with rituximab can help to control either CLL or Small lymphocytic lymphoma (SLL). The safety of the drug combination will also be studied.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 2CompletedFinished
20162017201820192020202120222023202420252026
First PostedJun 25, 2015
Enrollment StartJun 23, 2015
Primary CompletionAug 15, 2019
TodayJul 2, 2026
Enrollment to primary: 4.1 yearsPosted 11.0 years ago

Interventions

Lirilumabdrug

3 mg/kg by vein given on Day 1 of each 28 day cycle.

Rituximabdrug

375 mg/m2 by vein weekly for the first 4 weeks on Days 1,8, 15, and 22 of Cycle 1. After Cycle 1, given on Day 1 of Cycles 2 - 12.