At a glance
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The Effects of Cognitive Behavioral Therapy and Transcranial Current Stimulation (tDCS) on Chronic Lower Back Pain
In Brief
A Phase 3 clinical trial evaluating Cognitive Behavioral Therapy for Pain, Transcranial Direct Current Stimulation, and 1 other intervention for Chronic Low Back Pain and Opioid Use, Unspecified. Completed, enrolled 160 participants across 1 site.
Detailed Summary
The primary objective of this study is to evaluate the effects of cognitive-behavioral therapy in combination with transcranial direct current stimulation in (1) improving pain and functionality, (2) reducing severity of opioid use disorders, and (3) reducing impairment in associated mental health areas (e.g., depression, anxiety, PTSD, sleep). The investigators will also determine the effects of treatment on neural activity in cognitive and limbic brain regions involved in pain regulation using functional magnetic resonance imaging (fMRI), and examine its relationship to opioid use severity.
Study Details
Timeline
Interventions
Cognitive-behavioral therapy (CBT) for pain management takes an active problem-solving approach to tackling the many challenges associated with the experience of chronic pain. Rather than seeing ones self as helpless and disabled because of pain, CBT encourages individuals to take back control and re-engage in activities.
Electrical stimulation of the prefrontal cortex using 2mA of direct current
Sham stimulation of the left dorsolateral prefrontal cortex