CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 15 enrolled
Drug / intervention
SPK-9001biological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02484092
NCT02484092Phase 2Completed

Gene Therapy, Open-label, Dose-escalation Study of PF-06838435 (SPK-9001) [Adeno-associated Viral Vector With Human Factor IX Gene] in Subjects With Hemophilia B

Pfizer·interventional·Posted Jun 29, 2015·Updated Jun 16, 2020

In Brief

A Phase 2 clinical trial evaluating SPK-9001 for Hemophilia B. Completed, enrolled 15 participants across 10 sites in 2 countries.

Detailed Summary

A Phase 1/2, Open-Label, Non-Randomized, Dose-Escalation Study of SPK-9001 in Subjects with Hemophilia B.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHemophilia B
CountriesAustralia, United States
Collaborators--

Timeline

Phase 2CompletedFinished
20162017201820192020202120222023202420252026
First PostedJun 29, 2015
Enrollment StartNov 18, 2015
Primary CompletionApr 8, 2019
TodayJul 2, 2026
Enrollment to primary: 3.4 yearsPosted 11.0 years ago

Interventions

SPK-9001biological

A novel, bioengineered adeno-associated viral vector carrying human factor IX variant