CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 154 enrolled
Drug / intervention
Cyclophosphamide +4 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02486952
NCT02486952N/ACompleted

Open, Non-Interventional, Multicenter Trial of MabThera in Combination With CHOP (or CHOP-like) Chemotherapy in Patients With Aggressive B-Cell Lymphoma

Hoffmann-La Roche·observational·Posted Jul 1, 2015·Updated Feb 22, 2016

In Brief

An observational study evaluating Cyclophosphamide, Hydroxydaunorubicin, and 3 other interventions for Lymphoma, Lymphoma, Large B-Cell, Diffuse, Non-Hodgkin's Lymphoma, Lymphoma, Non Hodgkin, Relapsed or Refractory Diffuse Large B-Cell Lymphoma. Completed, enrolled 154 participants across 5 sites.

Detailed Summary

Evaluation of efficacy, safety profile and tolerability of rituximab (MabThera) in combination with chemotherapy in the treatment of Diffuse Large B-Cell Lymphoma (DLBCL). Participants, who were not treated previously for DLBCL, will receive MabThera in combination with Cyclophosphamide, Hydroxydaunorubicin, Oncovin, Prednisone (CHOP) or CHOP-like chemotherapy according to registered indication. Patients will be followed up for safety and efficacy evaluation in accordance with routine practice. The study will be non-interventional and by its design purely observational. All treatments prescribed during the observation period will be at the treating physician's discretion and will be prescribed according to package labeling, within approved indication and local approval status of respective drugs.

Study Details

Timeline

N/ACompletedFinished
20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJul 1, 2015
Enrollment StartAug 1, 2005
Primary CompletionJan 1, 2011
TodayJul 2, 2026
Enrollment to primary: 5.4 yearsPosted 11.0 years ago

Interventions

Cyclophosphamidedrug

Administered at the treating physician's discretion and according to package labeling, within approved indication and local approval status of the drug.

Hydroxydaunorubicindrug

Administered at the treating physician's discretion and according to package labeling, within approved indication and local approval status of the drug.

Oncovindrug

Administered at the treating physician's discretion and according to package labeling, within approved indication and local approval status of the drug.

Prednisonedrug

Administered at the treating physician's discretion and according to package labeling, within approved indication and local approval status of the drug.

Rituximabdrug

Administered at the treating physician's discretion and according to package labeling, within approved indication and local approval status of the drug.