CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 116 enrolled
Drug / intervention
Ketamine +2 moredrug
Likely dose
Ketamine 0.1mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02489630
NCT02489630Phase 4Completed
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Low Dose Ketamine as an Adjunct to Opiates for Acute Pain in the Emergency Department

Carilion Clinic·interventional·Posted Jul 3, 2015·Updated Mar 12, 2021

In Brief

A Phase 4 clinical trial evaluating Ketamine, Normal Saline, and 1 other intervention for Acute Pain and Pain. Completed, enrolled 116 participants.

Detailed Summary

This study investigates the use of low doses of ketamine, along with opiate pain medication, is more effective at controlling the acute pain of patients in the emergency department than opiate pain medication alone. In addition, this study examines whether patients treated with low doses of ketamine, along with opiate pain medication, will require less opiate pain medication to control their pain, and whether these patients are equally happy with their pain control as patients who receive only opiate pain medication.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAcute Pain, Pain
Countries--
CollaboratorsVirginia Polytechnic Institute and State University, University of Memphis

Timeline

Phase 4CompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedJul 3, 2015
Enrollment StartSep 1, 2013
Primary CompletionMar 1, 2015
TodayJul 2, 2026
Enrollment to primary: 1.5 yearsPosted 11.0 years ago

Interventions

Ketaminedrug

0.1mg/kg ketamine IV

Normal Salinedrug

1ml/kg normal saline placebo

opiate analgesicdrug

0.1mg/kg dose of morphine (or morphine equivalent) at 30 min time intervals based on patient pain score or more frequently upon request