CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 61 enrolled
Drug / intervention
FP-02.2 Vaccine +2 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02496897
NCT02496897Phase 1Completed

A Phase I, Randomized, Double-blind, Placebo-controlled, Multi-centre, Ascending-dose Trial to Evaluate the Safety, Tolerability and Immunogenicity of Vaccine FP-02.2 in HBeAg-negative Hepatitis B Patients as an add-on Treatment to Entecavir or Tenofovir.

Altimmune, Inc.·interventional·Posted Jul 14, 2015·Updated May 22, 2025

In Brief

A Phase 1 clinical trial evaluating FP-02.2 Vaccine, Placebo, and 1 other intervention for Hepatitis B. Completed, enrolled 61 participants across 21 sites in 2 countries.

Detailed Summary

This study evaluates the safety and immunogenicity of FP-02.2, a new therapeutic Hepatitis B vaccine, administered as an add-on therapy to entecavir or tenofovir.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHepatitis B
CountriesSouth Korea, United Kingdom
Collaborators--

Timeline

Phase 1CompletedFinished
20162017201820192020202120222023202420252026
First PostedJul 14, 2015
Enrollment StartJul 1, 2015
Primary CompletionOct 13, 2017
Study CompletionJun 5, 2018
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 11.0 years ago

Interventions

FP-02.2 Vaccinebiological

Synthetic Peptide Hepatitis B Vaccine

Placeboother

Placebo

IC31® Adjuvantother

IC31® Adjuvant