CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 100 enrolled
Drug / intervention
Ipilimumab +1 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02498600
NCT02498600Phase 2Completed

Phase II Randomized Trial of Nivolumab With or Without Ipilimumab in Patients With Persistent or Recurrent Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

National Cancer Institute (NCI)·interventional·Posted Jul 15, 2015·Updated Aug 29, 2025

In Brief

A Phase 2 clinical trial evaluating Ipilimumab and Nivolumab for Recurrent Fallopian Tube Carcinoma and 2 related conditions. Completed, enrolled 100 participants across 201 sites.

Detailed Summary

This randomized phase II trial studies how well nivolumab works with or without ipilimumab in treating patients with epithelial ovarian, primary peritoneal, or fallopian tube cancer that has not responded after prior treatment (persistent) or has come back (recurrent). Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
CollaboratorsNRG Oncology

Timeline

Phase 2CompletedFinished
20162017201820192020202120222023202420252026
First PostedJul 15, 2015
Enrollment StartAug 10, 2015
Primary CompletionSep 5, 2018
Study CompletionJul 26, 2025
TodayJul 2, 2026
Enrollment to primary: 3.1 yearsPosted 11.0 years ago

Interventions

Ipilimumabbiological

Given IV

Nivolumabbiological

Given IV