CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 15 enrolled
Drug / intervention
flavor and sweetener +3 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02499757
NCT02499757Phase 1Completed
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Does Sweet Taste Potentiate Nicotine Cue Reactivity?

Yale University·interventional·Posted Jul 16, 2015·Updated Mar 9, 2020

In Brief

A Phase 1 clinical trial evaluating flavor and sweetener, flavor and nicotine, and 2 other interventions for Healthy. Completed, enrolled 15 participants across 1 site.

Detailed Summary

The investigators' aim is to test the prediction that sweet taste perception enhances the ability of nicotine to induce neural plastic changes in brain reward circuits to increase the saliency, liking and brain reactivity to the sight and vaporized flavor of electronic cigarettes (e-cigarettes).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealthy
CountriesUnited States
CollaboratorsNational Institute on Drug Abuse (NIDA)

Timeline

Phase 1CompletedFinished
20162017201820192020202120222023202420252026
First PostedJul 16, 2015
Enrollment StartMay 1, 2015
Primary CompletionNov 1, 2015
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 11.0 years ago

Interventions

flavor and sweetenerdevice

maltol added as sweetener to e-cigarette with flavor

flavor and nicotinedevice

12 mg of nicotine added to e-cigarette with flavor

flavor, nicotine and sweetenerdevice

12 mg nicotine and maltol (sweetener) added to e-cigarette with flavor

flavordevice

flavored e-cigarette stand alone without added nicotine and maltol (sweetener)