CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 168 enrolled
Drug / intervention
Nifedipine GITS +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02499822
NCT02499822Phase 4Completed
CompareCT.gov

Short - Medium and Long Term Blood Pressure Variability in Essential Hypertensive Patients Treated With Nifedipine GITS or Ramipril - a Randomized Trial

Istituto Auxologico Italiano·interventional·Posted Jul 16, 2015·Updated Sep 30, 2021

In Brief

A Phase 4 clinical trial evaluating Nifedipine GITS and Ramipril for Hypertension and High Blood Pressure Variability. Completed, enrolled 168 participants across 3 sites in 3 countries.

Detailed Summary

The purpose of this study is 1. to compare the effects of nifedipine GITS and ramipril on blood pressure variability in subjects with elevated blood pressure variability. 2. to assess whether the degree of treatment-induced changes in blood pressure variability, is related to the degree of regression (or progression) of organ damage in heart, kidneys and carotid arteries.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHypertension, High Blood Pressure Variability
CountriesChina, Greece, Italy
CollaboratorsBayer

Timeline

Phase 4CompletedFinished
20162017201820192020202120222023202420252026
First PostedJul 16, 2015
Enrollment StartOct 1, 2015
Primary CompletionJul 3, 2020
Study CompletionNov 1, 2020
TodayJul 2, 2026
Enrollment to primary: 4.8 yearsPosted 11.0 years ago

Interventions

Nifedipine GITSdrug

Commercially available drug formulations are used. Study medication will be assumed in a single morning (7-10 a.m.) administration per os.

Ramiprildrug

Commercially available drug formulations are used. Study medication will be assumed in a single morning (7-10 a.m.) administration per os.