At a glance
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Alkaline Diet for Insulin Sensitivity
In Brief
A clinical study evaluating Sodium Bicarbonate Oral Capsule and Placebo for Dysglycemia and Type 2 Diabetes Mellitus. Completed, enrolled 32 participants across 1 site.
Detailed Summary
The purpose of this study is to test the effect of increasing the body pH acutely with an alkaline medication (sodium bicarbonate, NaHCO3, sodibic) on glucose metabolism post meal in non diabetic subjects with normal renal function. The investigators aim to determine whether there is an acute reduction in venous blood pH following a typical Western-style (high acid load) breakfast in healthy men and women, and whether this effect is attenuated by the concurrent administration of an alkaline medication. The effect on glucose metabolism, hunger/satiety and arterial stiffness post meal will be assessed.
Study Details
Timeline
Interventions
Sodium bicarbonate 1680 mg will be administered prior to the meal
Sodibic-matching placebo (Stenlake Compounding Chemist, NSW, Australia) will be administered prior to the meal on a different day 1 to 2 weeks apart