CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 21 enrolled
Drug / intervention
Manual blood pressure cuff inflation over brachial arterydevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02506062
NCT02506062N/ACompleted
CompareCT.gov

A Randomized, Single-blinded Placebo-controlled Trial of Ischemic Preconditioning in Raynaud's Phenomenon (RP)

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's·interventional·Posted Jul 22, 2015·Updated Aug 8, 2018

In Brief

A clinical study evaluating Manual blood pressure cuff inflation over brachial artery for Raynaud Disease and Raynaud's Phenomenon. Completed, enrolled 21 participants across 1 site.

Detailed Summary

This trial will test the efficacy of brief periods of controlled limb ischemia (remote ischemic preconditioning, RIPC) as an effective treatment of patients with Raynaud's Phenomenon (RP).The hypothesis of this trial is that due to its vasoprotective effects, RIPC would be more effective than placebo in the treatment of both primary and secondary RP, as defined by decreased frequency, duration, and severity of attacks. This trial was also designed to monitor the tolerance of RIPC in a rheumatologic population. Patients will not be required to stop any current treatment for RP.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsRaynaud Disease, Raynaud's Phenomenon
CountriesCanada
Collaborators--

Timeline

N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedJul 22, 2015
Enrollment StartJul 1, 2015
Primary CompletionAug 1, 2018
TodayJul 2, 2026
Enrollment to primary: 3.1 yearsPosted 10.9 years ago

Interventions

Manual blood pressure cuff inflation over brachial arterydevice

A manual blood pressure cuff (sphygmomanometer) is used in the study as a tourniquet in order to perform a controlled, consistent level of ischemia (200mmHg/active arm or 60 mmHg/placebo arm).