At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Phase I/II Trial of 8-Chloro-Adenosine in Relapsed or Refractory Acute Myeloid Leukemia
In Brief
A Phase 2 clinical trial evaluating 8-Chloroadenosine, Laboratory Biomarker Analysis, and 1 other intervention for Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome and 2 related conditions. Completed, enrolled 20 participants across 1 site.
Detailed Summary
This phase I/II trial studies the side effects and best dose of 8-chloroadenosine and to see how well it works in treating patients with acute myeloid leukemia that has returned after a period of improvement (relapsed) or does not respond to treatment (refractory). Drugs used in chemotherapy, such as 8-chloroadenosine, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.
Study Details
Timeline
Interventions
Given IV
Correlative studies
Correlative studies