CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 107 enrolled
Drug / intervention
GP2013 - A Proposed biosimilar rituximab +1 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02514772
NCT02514772Phase 3Completed

A Randomized, Double- Blind, Controlled, Parallel-group, Multicenter Study to Assess the Safety and Immunogenicity of Transitioning to GP2013 or Re-treatment With Rituxan® or MabThera® in Patients With Active Rheumatoid Arthritis, Previously Treated With Rituxan® or MabThera®

Sandoz·interventional·Posted Aug 4, 2015·Updated Dec 28, 2017

In Brief

A Phase 3 clinical trial evaluating GP2013 - A Proposed biosimilar rituximab and Originator rituximab - Rituxan ® or MabThera ® for Rheumatoid Arthritis. Completed, enrolled 107 participants across 65 sites in 4 countries.

Detailed Summary

The study objective is to identify potential safety risks of the transition from US-licensed Rituxan® or EU-approved MabThera® to GP2013 (proposed biosimilar product) as compared to continuous treatment with the originator product in terms of general safety and immunogenicity.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesGermany, Hungary, Poland, United States
CollaboratorsHexal AG

Timeline

Phase 3CompletedFinished
20162017201820192020202120222023202420252026
First PostedAug 4, 2015
Enrollment StartJul 1, 2015
Primary CompletionJul 1, 2016
Study CompletionOct 1, 2016
TodayJul 2, 2026
Enrollment to primary: 1 yearPosted 10.9 years ago

Interventions

GP2013 - A Proposed biosimilar rituximabbiological

Originator rituximab - Rituxan ® or MabThera ®biological