CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 41 enrolled
Drug / intervention
MMBdrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02515630
NCT02515630Phase 2Completed

A Phase 2, Open-label, Translational Biology Study of Momelotinib in Transfusion-Dependent Subjects With Primary Myelofibrosis (PMF) or Post-polycythemia Vera or Post-essential Thrombocythemia Myelofibrosis (Post-PV/ET MF)

Sierra Oncology LLC - a GSK company·interventional·Posted Aug 5, 2015·Updated Jun 18, 2023

In Brief

A Phase 2 clinical trial evaluating MMB for Primary Myelofibrosis (PMF) and 2 related conditions. Completed, enrolled 41 participants across 13 sites in 2 countries.

Detailed Summary

This study will evaluate the transfusion independence response rate in transfusion-dependent adults with myelofibrosis after treatment with momelotinib (MMB).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCanada, United States
Collaborators--

Timeline

Phase 2CompletedFinished
20162017201820192020202120222023202420252026
First PostedAug 5, 2015
Enrollment StartJan 29, 2016
Primary CompletionJul 18, 2017
Study CompletionAug 15, 2017
TodayJul 2, 2026
Enrollment to primary: 1.5 yearsPosted 10.9 years ago

Interventions

MMBdrug

Momelotinib (MMB) tablet administered orally once daily