CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 5 enrolled
Drug / intervention
Liraglutidedrug
Likely dose
Liraglutide 0.6 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02516657
NCT02516657Phase 3Completed

Effect of Liraglutide on Glycemic Control, Glucagon Secretion and Inflammatory Markers in Adolescents With Type 1 Diabetes Mellitus

University at Buffalo·interventional·Posted Aug 6, 2015·Updated Apr 20, 2025

In Brief

A Phase 3 clinical trial evaluating Liraglutide for Type 1 Diabetes. Completed, enrolled 5 participants across 1 site.

Detailed Summary

The purpose of this study is to study the effect of a liraglutide, a glucagon-like peptide agonist, on post-meal blood glucose concentrations, glucagon levels, mean weekly blood sugars, and insulin doses in adolescents with Type 1 diabetes. Type 1 diabetes is an autoimmune disease that is usually diagnosed before the age of 20. Individuals with this disease are completely dependent on insulin for survival. While significant advances have been made in technological support for improving diabetes control, insulin remains the only effective treatment for Type 1 diabetes. Liraglutide is a long-acting glucagon-like peptide-1 analog. This drug is approved for the treatment of Type 2 diabetes in adults. This study will test the effect of liraglutide on blood sugar control in adolescents with Type 1 diabetes.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsType 1 Diabetes
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedAug 6, 2015
Enrollment StartMay 1, 2012
Primary CompletionAug 3, 2022
Study CompletionAug 3, 2023
TodayJul 2, 2026
Enrollment to primary: 10.3 yearsPosted 10.9 years ago

Interventions

Liraglutidedrug

Liraglutide 0.6 mg