CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 182 enrolled
Drug / intervention
Ketamine IV 1mg/kg +2 moredrug
Likely dose
Ketamine IV 1mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02519595
NCT02519595Phase 4Completed
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Optimal Dosing of Ketamine for Procedural Sedation and Analgesia in Children

Children's Hospital of Michigan·interventional·Posted Aug 11, 2015·Updated Oct 12, 2016

In Brief

A Phase 4 clinical trial evaluating Ketamine IV 1mg/kg, Ketamine IV 1.5mg/kg, and 1 other intervention for Moderate, Deep Sedation. Completed, enrolled 182 participants.

Detailed Summary

There is a wide variation of published IV ketamine dosing regimens used for procedural sedation in children in the Emergency Department (ED). The purpose of the study was to compare the efficacy, duration of sedation and adverse events between the three commonly administered doses of IV ketamine (1 mg/kg, 1.5 mg/kg and 2 mg/kg) using the traditional administration method of 30-60 second infusion for ED sedation in children.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsModerate, Deep Sedation
Countries--
Collaborators--

Timeline

Phase 4CompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedAug 11, 2015
Enrollment StartAug 1, 2010
Primary CompletionAug 1, 2012
TodayJul 2, 2026
Enrollment to primary: 2 yearsPosted 10.9 years ago

Interventions

Ketamine IV 1mg/kgdrug

Intervention: Ketamine IV 1mg/kg

Ketamine IV 1.5mg/kgdrug

Intervention: Ketamine IV 1.5 mg/kg

Ketamine IV 2mg/kgdrug

Intervention: Ketamine IV 2 mg/kg