CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 15 enrolled
Drug / intervention
Ketamine +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02522377
NCT02522377N/ACompleted
CompareCT.gov

Administration of Subanesthetic Dose of Ketamine and Electroconvulsive Treatment on Alternate Week Days in Patients With Treatment Resistant Depression: A Double Blind Placebo Controlled Trial

The Cleveland Clinic·interventional·Posted Aug 13, 2015·Updated Aug 29, 2019

In Brief

A clinical study evaluating Ketamine and Midazolam for Treatment Resistant Depression and 2 related conditions. Completed, enrolled 15 participants across 1 site.

Detailed Summary

In this proof of concept study, the investigators plan to administer iv ketamine interleaved with ECT days. Patients with treatment resistant depression who are deemed to be eligible for ECT treatment will randomly be assigned to either ketamine or active placebo.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsTreatment Resistant Depression, Major Depressive Disorder, Severe Depression
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedAug 13, 2015
Enrollment StartAug 1, 2015
Primary CompletionMar 1, 2018
TodayJul 2, 2026
Enrollment to primary: 2.6 yearsPosted 10.9 years ago

Interventions

Ketaminedrug

inter venous injections

Midazolamdrug

inter venous injections