CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 10 enrolled
Drug / intervention
Propofol +3 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02527083
NCT02527083Phase 4Completed

Influence of Anesthetic Technique on Acute and Chronic Neuropathic Pain

VA Pittsburgh Healthcare System·interventional·Posted Aug 18, 2015·Updated Dec 31, 2025

In Brief

A Phase 4 clinical trial evaluating Propofol, Sevoflurane, and 2 other interventions for Acute Pain and 4 related conditions. Completed, enrolled 10 participants.

Detailed Summary

Research suggests that the type of anesthesia used for surgery may affect intraoperative stress hormone levels. There is also data to support that an increased level of stress hormones leads to increased pain after surgery. The primary aim of this study is to determine the effect of anesthesia type on long term pain after hernia surgery. In this study, patients undergoing inguinal hernia repair will be randomized to an anesthetic group, either Total Intravenous Anesthesia (TIVA) maintained with propofol or Balanced Inhaled Anesthesia (BIA) maintained with sevoflurane. This will allow us to look at any differences in short and long-term pain after hernia repair depending on type of anesthesia received.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
Countries--
Collaborators--

Timeline

Phase 4CompletedFinished
201520162017201820192020202120222023202420252026
First PostedAug 18, 2015
Enrollment StartJan 1, 2015
Primary CompletionJun 1, 2019
TodayJul 2, 2026
Enrollment to primary: 4.4 yearsPosted 10.9 years ago

Interventions

Propofoldrug

Sevofluranedrug

Remifentanildrug

Ketaminedrug