CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 70 enrolled
Drug / intervention
QR-010 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02532764
NCT02532764Phase 2Completed

Phase 1b, Randomized, Double-blind, Placebo-controlled, Dose Escalation Study to Evaluate the Safety, Tolerability and Pharmacokinetics of QR-010 in Subjects With Homozygous ΔF508 Cystic Fibrosis

ProQR Therapeutics·interventional·Posted Aug 26, 2015·Updated Feb 6, 2019

In Brief

A Phase 2 clinical trial evaluating QR-010 and Placebo for Cystic Fibrosis. Completed, enrolled 70 participants across 27 sites in 10 countries.

Detailed Summary

A randomized, double-blind, placebo-controlled study of single and multiple ascending doses of QR-010 in adults homozygous for ΔF508 Cystic Fibrosis.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCystic Fibrosis
CountriesBelgium, Canada, Czechia, Denmark, France, Germany, Italy, Spain, United Kingdom, United States
CollaboratorsEuropean Commission

Timeline

Phase 2CompletedFinished
20162017201820192020202120222023202420252026
First PostedAug 26, 2015
Enrollment StartJun 1, 2015
Primary CompletionSep 14, 2017
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 10.8 years ago

Interventions

QR-010drug

Single-stranded RNA antisense oligonucleotide in aqueous solution for oral inhalaton

Placebodrug

Normal Saline