CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 294 enrolled
Drug / intervention
Subluxation +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02535819
NCT02535819N/ACompleted

Endothelial Cell Loss After Phacoemulsification Intra and Supracapsular

Centre Hospitalier Régional Metz-Thionville·interventional·Posted Aug 31, 2015·Updated Jun 24, 2026

In Brief

A clinical study evaluating Subluxation and Divide and Conquer for Cataracts. Completed, enrolled 294 participants across 1 site.

Detailed Summary

Cataract is the clouding of the lens of the eye, which initially prevents clear vision and eventually progresses to blindness if left untreated. Cataract remains the leading cause of blindness and an important cause of visual impairment across the globe. Cataract surgery by ultrasonic phacoemulsification is the most common surgery practiced in France (600 000/year) Two sub-categories of phacoemulsification coexist : Endocapsulars techniques represented by Divide-and-Conquer and Phaco-Chop ; and Supracapsular techniques mainly represented by Subluxation (similar to Tilt-and-Tumble) The corneal endothelium plays an important role in maintaining the dehydrated state and the transparency of the cornea. Some degree of endothelial cell loss invariably occurs in all types of cataract surgery but the amount of endothelial cell loss may varies with the type of surgical technique The aim of the study is to evaluate the density of the central corneal endothelial cells before and after cataract surgery comparing two phacoemulsification techniques (Divide-and-Conquer vs Subluxation)

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCataracts
CountriesFrance
Collaborators--

Timeline

N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedAug 31, 2015
Enrollment StartJun 1, 2015
Primary CompletionSep 1, 2017
Study CompletionMay 1, 2018
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 10.8 years ago

Interventions

Subluxationprocedure

One pole of The nucleus is hydrodissected until it lilts above the capsular bag. The tilted nucleus is rotated to face the incision and remaining half nucleus is then tumbled and emulsification continues from the opposite equator outside in until complete

Divide and Conquerprocedure

Cataract nucleus is fragmented into 4 pieces then aspirated by ultrasonic vibration