At a glance
ClinicalIndex Comparison RecordN/ACompleted· 6 enrolled
Drug / intervention
blood samplesbiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Characterization of Non-canonical Way in Inflammasome Monocytes of Patients With Severe Sepsis
In Brief
An observational study evaluating blood samples for Severe Sepsis. Completed, enrolled 6 participants across 1 site.
Detailed Summary
Activation of caspase-4 and human caspase-5 (orthologs of caspase-11 in mice) in innate immune cells.
Study Details
Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsSevere Sepsis
CountriesFrance
CollaboratorsInstitut Pasteur, Agency for Science, Technology and Research
Timeline
N/ACompletedFinished
201520162017201820192020202120222023202420252026
Enrollment StartSep 2014
Primary CompletionDec 2014
First PostedSep 2015
TodayJul 2026
First PostedSep 2, 2015
Enrollment StartSep 1, 2014
Primary CompletionDec 1, 2014
TodayJul 2, 2026
Enrollment to primary: 3 monthsPosted 10.8 years ago
Interventions
blood samplesbiological
Isolation and stimulation of monocytes, preparation of cell lysates, measurement of cytokine production, Western blot