CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 64 enrolled
Drug / intervention
Methylprednisolone +1 moredrug
Likely dose
Methylprednisolone 125 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02542592
NCT02542592Phase 3Completed
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Effect of Preoperative Intravenous High Dose Methylprednisolone on Immune Signaling in Patients Scheduled for Total Hip-arthroplasty

Rigshospitalet, Denmark·interventional·Posted Sep 7, 2015·Updated Jan 18, 2017

In Brief

A Phase 3 clinical trial evaluating Methylprednisolone and Isotonic Sodium Chloride for Osteoarthrosis. Completed, enrolled 64 participants across 1 site.

Detailed Summary

The study evaluates the pathophysiological effects of a single dose Methylprednisolone administered prior to total hip-arthroplasty (THA) surgery. The investigators examine the effect on immune signaling and recovery after surgery. Half of participants will receive intravenous Solu-Medrol 125 mg, while the other half will receive placebo. The investigators hypothesize that the group receiving Methylprednisolone will experience a positive modulation of the immune response and an enhanced recovery.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsOsteoarthrosis
CountriesDenmark
CollaboratorsBispebjerg Hospital

Timeline

Phase 3CompletedFinished
20162017201820192020202120222023202420252026
First PostedSep 7, 2015
Enrollment StartSep 1, 2015
Primary CompletionJan 1, 2017
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 10.8 years ago

Interventions

Methylprednisolonedrug

Comparison of preoperative single high dose of Methylprednisolone 125 mg iv. and isotonic Sodium Chloride (placebo)

Isotonic Sodium Chloridedrug

Placebo