CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 239 enrolled
Drug / intervention
Liposomal Bupivacaine +5 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02543801
NCT02543801Phase 4Completed

A Prospective, Randomized Clinical Trial of Two Periarticular Multimodal Drug Injections in Total Hip and Knee Arthroplasty

Kootenai Health·interventional·Posted Sep 7, 2015·Updated Oct 18, 2019

In Brief

A Phase 4 clinical trial evaluating Liposomal Bupivacaine, Ropivacaine, and 4 other interventions for Total Hip and Knee Arthroplasty. Completed, enrolled 239 participants.

Detailed Summary

This study evaluates two routinely used drug combinations for periarticular injection following total hip and knee arthroplasty for pain control. One group will receive liposomal bupivacaine, bupivacaine, clonidine, epinephrine and ketorolac. The other group will receive ropivacaine, clonidine, epinephrine and ketorolac.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
Countries--
Collaborators--

Timeline

Phase 4CompletedFinished
20162017201820192020202120222023202420252026
First PostedSep 7, 2015
Enrollment StartJan 25, 2016
Primary CompletionAug 21, 2018
TodayJul 2, 2026
Enrollment to primary: 2.6 yearsPosted 10.8 years ago

Interventions

Liposomal Bupivacainedrug

Periarticular injection

Ropivacainedrug

Periarticular injection

Bupivacainedrug

Included as an element of the Liposomal bupivacaine intervention periarticular injection

Clonidinedrug

Included as an element of both interventions as a standard of care periarticular injection

Ketorolacdrug

Included as an element of both interventions as a standard of care periarticular injection

Epinephrinedrug

Included as an element of both interventions as a standard of care periarticular injection