At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Comparing the Efficacy and Impact on Gastrointestinal Microbiome of Reverse Hybrid Therapy and Bismuth Quadruple Therapy in Helicobacter Pylori Eradication
In Brief
A clinical study evaluating pantoprazole+bismuth+tetra+metro and (panto+amox+clar+metr)+(panto+amox) for Helicobacter Pylori Infection. Completed, enrolled 352 participants across 1 site.
Detailed Summary
Reverse hybrid therapy achieves a higher eradication rate than bismuth quadruple therapy remained unanswered.
Study Details
Timeline
Interventions
pantoprazole 40 mg twice daily, bismuth subcitrate 120 mg four times daily, and tetracycline 500 mg four times daily, and metronidazole 250 mg four times daily for 14 days
a 7-day quadruple regimen with pantoprazole 40 mg twice daily, amoxicillin 1 g twice daily, clarithromycin 500 mg twice daily, and metronidazole 500 mg twice daily, followed by a 7-day dual regimen with pantoprazole 40 mg twice daily and amoxicillin 1 g twice daily