CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 117 enrolled
Drug / intervention
PRM-151 +1 morebiological
Likely dose
PRM-151 10 mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02550873
NCT02550873Phase 2Completed

A Phase 2 Trial to Evaluate the Efficacy of PRM-151 in Subjects With Idiopathic Pulmonary Fibrosis (IPF)

Hoffmann-La Roche·interventional·Posted Sep 16, 2015·Updated May 2, 2022

In Brief

A Phase 2 clinical trial evaluating PRM-151 and placebo for Idiopathic Pulmonary Fibrosis. Completed, enrolled 117 participants across 18 sites in 7 countries.

Detailed Summary

This study is a Phase 2, randomized, double-blind, placebo controlled, pilot study designed to evaluate the efficacy and safety of PRM-151 administered through Week 24 to subjects with IPF.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCzechia, Germany, Italy, Netherlands, Spain, Switzerland, United States
Collaborators--

Timeline

Phase 2CompletedFinished
20162017201820192020202120222023202420252026
First PostedSep 16, 2015
Enrollment StartSep 1, 2015
Primary CompletionMay 2, 2017
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 10.8 years ago

Interventions

PRM-151biological

PRM 151 10 mg/kg IV infusion over 60 minutes days 1, 3, and 5, then one infusion every 4 weeks

placeboother

Placebo IV infusion over 60 minutes on days 1, 3, and 5, then one infusion every 4 weeks