CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 67 enrolled
Drug / intervention
ACP-01 +1 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02551679
NCT02551679Phase 2Completed

A Randomized Double Blind Placebo Controlled Clinical Study to Assess Blood-Derived Autologous Angiogenic Cell Precursor Therapy in Patients With Critical Limb Ischemia (ACP-CLI)

Hemostemix·interventional·Posted Sep 16, 2015·Updated Nov 28, 2023

In Brief

A Phase 2 clinical trial evaluating ACP-01 and Placebo for Critical Limb Ischemia. Completed, enrolled 67 participants across 19 sites in 2 countries.

Detailed Summary

The primary objective of this study is to determine the efficacy and safety of intramuscular injection of ACP-01, comprised of blood-derived autologous ACPs, in subjects with critical limb ischemia who are receiving standard of care therapy and have no endovascular or surgical revascularization options.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCanada, United States
Collaborators--

Timeline

Phase 2CompletedFinished
201520162017201820192020202120222023202420252026
First PostedSep 16, 2015
Enrollment StartAug 1, 2014
Primary CompletionApr 1, 2020
Study CompletionApr 1, 2021
TodayJul 2, 2026
Enrollment to primary: 5.7 yearsPosted 10.8 years ago

Interventions

ACP-01biological

Injection into lower extremity

Placebobiological

Injection into lower extremity