CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 40 enrolled
Drug / intervention
Budesonide +5 moredrug
Likely dose
Prednisone 40 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02562924
NCT02562924N/ACompleted

An Open-label, Prospective, Randomized, Pilot Clinical Study to Study the Efficacy of MEDIHONEY® Rinses Compared to Intranasal Corticosteroid Rinses in Chronic Rhinosinusitis With Nasal Polyposis After Functional Endoscopic Sinus Surgery

University of Vermont Medical Center·interventional·Posted Sep 29, 2015·Updated Oct 16, 2019

In Brief

A clinical study evaluating MEDIHONEY®, Budesonide, and 4 other interventions for Chronic Sinusitis and Nasal Polyposis. Completed, enrolled 40 participants across 1 site.

Detailed Summary

This study will assess the effectiveness of MEDIHONEY® sinus rinses (alone or in combination with intranasal corticosteroids) vs. intranasal corticosteroid sinus rinses on mucosal healing and polyp recurrence in the post-operative period following functional endoscopic sinus surgery.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedSep 29, 2015
Enrollment StartNov 1, 2015
Primary CompletionDec 1, 2017
TodayJul 2, 2026
Enrollment to primary: 2.1 yearsPosted 10.8 years ago

Interventions

MEDIHONEY®device

MEDIHONEY® is a seminatural product with antibacterial and anti-inflammatory properties

Budesonidedrug

Topical steroid

Normal saline sinus rinsedrug

8 oz or 4 oz of normal saline with NeilMed sinus rinse bottle

Prednisonedrug

Post-operatively, 40 mg daily for 7 days

Endoscopic sinus surgeryprocedure

Endoscopic sinus surgery to debride polyps and establish adequate sinus drainage

nasal saline spraydrug

saline nasal mist every hour while awake