At a glance

ClinicalIndex Comparison Record

N/ACompleted· 35 enrolled

Drug / intervention

teriparatide +1 moredrug

Likely dose

teriparatide 20 microgramfrom record

Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02563353

NCT02563353N/ACompleted

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PTH and Vibration in OSteoporosis (PaVOS) Study

Odense University Hospital·interventional·Posted Sep 30, 2015·Updated Sep 18, 2020

In Brief

A clinical study evaluating whole-body vibration and teriparatide for Osteoporosis. Completed, enrolled 35 participants across 1 site.

Detailed Summary

Objective: This is a randomized controlled trial (RCT) in osteoporosis patients randomized to standard parathyroid hormone (PTH) treatment alone or to standard PTH treatment and Whole-body vibration (WBV). PTH is an effective but expensive anabolic treatment for osteoporosis. WBV stimulates muscles and bones. A combined treatment might have synergistic or additive beneficial effects on bone, reducing fracture risk making treatment more effective and cost-effective. A beneficial effect on muscles and thereby falls risk of WBV may improve fracture risk even further. If the results of this pilot study are promising then a strong case can be made for a large multi-centre RCT using strong endpoints including fractures and falls.

Study Details

Study Typeinterventional

Allocation--

Masking--

Primary Purpose--

ConditionsOsteoporosis

CountriesDenmark

CollaboratorsUniversity of Southern Denmark, Copenhagen University Hospital, Denmark, Esbjerg Hospital - University Hospital of Southern Denmark, Sygehus Lillebaelt, Odense Patient Data Explorative Network, Region of Southern Denmark

Timeline

N/ACompletedFinished

20162017201820192020202120222023202420252026

First PostedSep 2015

Enrollment StartNov 2015

Primary CompletionNov 2018

Study CompletionNov 2019

TodayJul 2026

First PostedSep 30, 2015

Enrollment StartNov 1, 2015

Primary CompletionNov 1, 2018

Study CompletionNov 1, 2019

TodayJul 2, 2026

Enrollment to primary: 3 yearsPosted 10.8 years ago

Interventions

whole-body vibrationother

Whole-body vibration on vibration platforms. 30-40 Hertz, from 2 mm (low) to 4 mm (high) amplitude, 1 minutes x 6 with 1 minute break between. 3 times a week.

teriparatidedrug

Teriparatide, 20 microgram/day. 24 months of treatment.