At a glance
ClinicalIndex Comparison RecordPhase 1Completed· 18 enrolled
Drug / intervention
Rosuvastatin +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
The Effect of Different Doses of Metformin or Furosemide on Rosuvastatin Pharmacokinetics Following Oral Administration in Healthy Male Subjects (an Open-label, Randomised, Single-dose, Six-way Crossover Study)
In Brief
A Phase 1 clinical trial evaluating Rosuvastatin, Metformin HCl, and 1 other intervention for Healthy. Completed, enrolled 18 participants across 1 site.
Detailed Summary
The primary objective of this trial is to investigate the relative bioavailability of rosuvastatin when given alone (Reference treatment, R) compared to when given together with one of the three different doses of metformin (10 mg, Test treatment 1 (T1); 50 mg (T2); 500 mg (T3)) or one of the two doses of furosemide (1 mg (T4); 5 mg (T5)).
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealthy
CountriesGermany
Collaborators--
Timeline
Phase 1CompletedFinished
20162017201820192020202120222023202420252026
Enrollment StartOct 2015
First PostedOct 2015
Primary CompletionDec 2015
Study CompletionDec 2015
TodayJul 2026
First PostedOct 14, 2015
Enrollment StartOct 12, 2015
Primary CompletionDec 9, 2015
Study CompletionDec 14, 2015
TodayJul 2, 2026
Enrollment to primary: 2 monthsPosted 10.7 years ago
Interventions
Rosuvastatindrug
Metformin HCldrug
Furosemidedrug