At a glance
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Protocol for Staged Stereotactic Radiosurgery for Large Arteriovenous Malformations
In Brief
A clinical study evaluating Fractionated stereotactic radiosurgery and Leskell gamma unit for Intracranial Arteriovenous Malformations (AVM). Completed, enrolled 18 participants.
Detailed Summary
Stereotactic radiosurgery is a well established treatment option for arteriovenous malformations (AVMs). The potential complications related to radiosurgery are well documented and are predominately related to radiation effects to the surrounding brain parenchyma. These risks increase with larger lesions, requiring a concommitant reduction in the amount of radiation that can be delivered. This reduction in radiation dose decreases the efficacy of treatment. The broad, long-term objectives of this proposal are 1) to determine the role of fractionated stereotactic radiosurgery in the treatment of large (\>10cc) AVMs; 2) to evaluate the complication rates related to fractionating these doses compared to conventional stereotactic treatment 3) to evaluate the success rate of treating large AVMs with this protocol.
Study Details
Timeline
Interventions
FDA approved device