CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 143 enrolled
Drug / intervention
Ipragliflozin +2 moredrug
Likely dose
Ipragliflozin 50 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02577003
NCT02577003Phase 3Completed

A Phase III, Multicenter, Randomized, Placebo-Controlled, Parallel-Group, Double-Blind Trial to Assess the Safety and Efficacy of Addition of Ipragliflozin in Japanese Patients With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Sitagliptin Monotherapy in Addition to Diet and Exercise Therapy

Merck Sharp & Dohme LLC·interventional·Posted Oct 15, 2015·Updated Sep 4, 2018

In Brief

A Phase 3 clinical trial evaluating Ipragliflozin, Placebo, and 1 other intervention for Type 2 Diabetes Mellitus. Completed, enrolled 143 participants.

Detailed Summary

This is a study to assess the safety and efficacy of the addition of ipragliflozin once daily in Japanese participants with Type 2 diabetes mellitus (T2DM) who have inadequate glycemic control on sitagliptin, diet, and exercise therapy. The primary hypothesis for this study is that the addition of ipragliflozin compared with placebo provides greater reduction in hemoglobin A1C (HbA1c) as assessed by change from baseline at Week 24.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
Countries--
Collaborators--

Timeline

Phase 3CompletedFinished
20162017201820192020202120222023202420252026
First PostedOct 15, 2015
Enrollment StartNov 9, 2015
Primary CompletionNov 25, 2016
TodayJul 2, 2026
Enrollment to primary: 1.0 yearsPosted 10.7 years ago

Interventions

Ipragliflozindrug

50 mg tablet administered orally

Placebodrug

Placebo to ipragliflozin tablet administered orally

Sitagliptindrug

Background medication; 50 mg tablet administered orally