CI

At a glance

ClinicalIndex Comparison Record
Phase 2Active· 100 target
Drug / intervention
Vaseline Petroleum Jelly +1 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02577120
NCT02577120Phase 2ActiveOn TrackUpdated 9mo ago

Wound Healing Endpoint and Recurrence

Sashwati Roy·interventional·Posted Oct 16, 2015·Updated Sep 26, 2025

In Brief

A Phase 2 clinical trial evaluating Epiceram Skin Barrier Function and Vaseline Petroleum Jelly for Chronic Wound and 6 related conditions. Active but no longer recruiting, targeting 100 participants across 3 sites.

Detailed Summary

This study is a continuation of a previously approved protocol conducted at Ohio State University and Indiana University. The first two aims of the original protocol have been completed, and this protocol will finish enrollment for the third aim, comparing Hi TEWL and Low TEWL measurements, and whether a HiTEWLmeasurement indicates a seemingly healed wound is more likely to recur/reopen toa new wound. Of the 105 desired subjects, 62 subjects have already been recruited and completed their study participation at the previous university. 43 additional subjects will be recruited to complete the enrollment goal here at the University of Pittsburgh.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2Active
2016201720182019202020212022202320242025202620272028202920302031203220332034
First PostedOct 16, 2015
Enrollment StartJan 8, 2019
Primary CompletionFeb 1, 2029
Study CompletionFeb 1, 2034
TodayJul 2, 2026
Enrollment to primary: 10.1 yearsPosted 10.7 years agoPrimary completion in 2.6 years

Interventions

Epiceram Skin Barrier Functiondevice

Epiceram is a non-sterile, viscous, lipid-rich emulsion

Vaseline Petroleum Jellybiological

A skin protectant used for temporarily protecting minor cuts, scraps, burns, and helps to protect and help relieve chapped or cracked skin and lips.