At a glance

ClinicalIndex Comparison Record

N/ACompleted· 118 enrolled

Drug / intervention

Hydrocortisone +1 moredrug

Likely dose

Hydrocortisone 200 mgfrom record

Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02580240

NCT02580240N/ACompleted

Compare CT.gov

Early Initiation of Low-dose Hydrocortisone Treatment for Septic Shock in Adults: a Randomized Clinical Trial

Northern Jiangsu People's Hospital·interventional·Posted Oct 20, 2015·Updated Aug 7, 2017

In Brief

A clinical study evaluating Hydrocortisone and saline for Septic Shock. Completed, enrolled 118 participants across 1 site.

Detailed Summary

The purpose of this study : 1）to determine whether hydrocortisone is effective in the treatment of septic shock and 2) to identify the role of timing of low dose hydrocortisone administration in septic shock patients.

Study Details

Study Typeinterventional

Allocation--

Masking--

Primary Purpose--

ConditionsSeptic Shock

CountriesChina

Collaborators--

Timeline

N/ACompletedFinished

20162017201820192020202120222023202420252026

Enrollment StartSep 2015

First PostedOct 2015

Primary CompletionSep 2016

Study CompletionDec 2016

TodayJul 2026

First PostedOct 20, 2015

Enrollment StartSep 1, 2015

Primary CompletionSep 1, 2016

Study CompletionDec 1, 2016

TodayJul 2, 2026

Enrollment to primary: 1 yearPosted 10.7 years ago

Interventions

Hydrocortisonedrug

Hydrocortisone was administered 200 mg/d as a continuous infusion for 6d, then tapered off. Once all vasopressors were discontinued, the taper protocol was initiated (half dose for three days, then quarter dose for three days and then stopped).

salinedrug

Vials containing normal saline as placebo were identical to those containing hydrocortisone. Placebo administration procedures were similar.