CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 23 enrolled
Drug / intervention
MEDI4736 in combination with nab-paclitaxel and gemcitabine +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02583477
NCT02583477Phase 2Completed

A Phase Ib and II Open-Label, Multi-Center Study of MEDI4736 Evaluated in Different Combinations in Patients With Metastatic Pancreatic Ductal Adenocarcinoma

AstraZeneca·interventional·Posted Oct 22, 2015·Updated Aug 14, 2019

In Brief

A Phase 2 clinical trial evaluating MEDI4736 in combination with nab-paclitaxel and gemcitabine and MEDI4736 in combination with AZD5069 for Metastatic Pancreatic Ductal Adenocarcinoma. Completed, enrolled 23 participants across 7 sites in 2 countries.

Detailed Summary

A Phase Ib and II Open-Label, Multi-Center Study of MEDI4736 Evaluated in Different Combinations (with chemotherapy or AZD5069) in Patients with Metastatic Pancreatic Ductal Adenocarcinoma

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited Kingdom, United States
Collaborators--

Timeline

Phase 2CompletedFinished
20162017201820192020202120222023202420252026
First PostedOct 22, 2015
Enrollment StartMar 25, 2016
Primary CompletionJul 9, 2018
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 10.7 years ago

Interventions

MEDI4736 in combination with nab-paclitaxel and gemcitabinedrug

MEDI4736 in combination with nab-paclitaxel + gemcitabine chemotherapy regimen via IV infusion

MEDI4736 in combination with AZD5069drug

MEDI4736 via IV infusion and oral AZD5069