CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 106 enrolled
Drug / intervention
DS-1040b +1 moredrug
Likely dose
DS-1040b 0.6 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02586233
NCT02586233Phase 2Completed

A Phase 1b/2, Multi-Center, Double-Blind (Principal Investigators and Study Subjects Blinded, Sponsor Unblinded), Placebo-Controlled, Randomized, Single-Ascending Dose Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of DS-1040b in Subjects With Acute Ischemic Stroke

Daiichi Sankyo·interventional·Posted Oct 26, 2015·Updated Sep 9, 2020

In Brief

A Phase 2 clinical trial evaluating DS-1040b and Placebo for Acute Ischemic Stroke and Thrombotic Disease. Completed, enrolled 106 participants across 55 sites in 11 countries.

Detailed Summary

This is a Phase 1b/2, double-blind (study participants and Investigators), placebo-controlled, randomized, single-ascending dose, multi-center study to assess the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of DS-1040b in participants with Acute Ischemic Stroke (AIS).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, Czechia, France, Germany, Italy, Slovakia, South Korea, Spain, Taiwan, United Kingdom, United States
Collaborators--

Timeline

Phase 2CompletedFinished
20162017201820192020202120222023202420252026
First PostedOct 26, 2015
Enrollment StartSep 1, 2015
Primary CompletionAug 13, 2019
TodayJul 2, 2026
Enrollment to primary: 3.9 yearsPosted 10.7 years ago

Interventions

DS-1040bdrug

DS-1040b for IV infusion (0.6 mg to 9.6 mg) over 6-hour period

Placebodrug

0.9% sodium chloride (placebo comparator) for IV infusion over 6-hour period