CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 258 enrolled
Drug / intervention
Standard Oral Hygiene +2 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02589938
NCT02589938N/ACompleted
CompareCT.gov

A Phase III Prospective Randomized Trial of Acupuncture for Treatment of Radiation-Induced Xerostomia in Patients With Head and Neck Cancer

Wake Forest University Health Sciences·interventional·Posted Oct 28, 2015·Updated Feb 27, 2026

In Brief

A clinical study evaluating Standard Oral Hygiene, Standard Oral Hygiene + True Acupuncture, and 1 other intervention for Radiation-Induced Xerostomia and 3 related conditions. Completed, enrolled 258 participants across 36 sites.

Detailed Summary

This study is being done to find out what effects, good and/or bad, acupuncture has on participants and their xerostomia caused by radiation therapy for the treatment of the cancer.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsRadiation-Induced Xerostomia, Head and Neck Cancer, Radiation Toxicity, Oral Complications of Chemotherapy and Head/Neck Radiation
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedOct 28, 2015
Enrollment StartNov 11, 2012
Primary CompletionJul 29, 2022
TodayJul 2, 2026
Enrollment to primary: 9.7 yearsPosted 10.7 years ago

Interventions

Standard Oral Hygieneother

Oral hygiene care provided per individual institutions standard of care.

Standard Oral Hygiene + True Acupunctureother

Oral hygiene care provided per individual institutions standard of care. 14 true acupoint sites will be selected and applied to each participant for 20 minutes at each session. There will be 2 sessions a week for 8 weeks.

Standard Oral Hygiene + Sham Acupunctureother

Oral hygiene care provided per individual institutions standard of care. 14 sham acupoint sites will be selected and applied to each participant for 20 minutes at each session. There will be 2 sessions a week for 8 weeks.