CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 41 enrolled
Drug / intervention
Secukinumab +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02594098
NCT02594098Phase 2Completed

A Pilot Study to Evaluate the Efficacy and Safety of Secukinumab in the Treatment of Moderate to Severe Atopic Dermatitis

Icahn School of Medicine at Mount Sinai·interventional·Posted Nov 2, 2015·Updated Jun 12, 2019

In Brief

A Phase 2 clinical trial evaluating Secukinumab and Placebo for Atopic Dermatitis. Completed, enrolled 41 participants across 1 site.

Detailed Summary

Atopic Dermatitis, also known as atopic eczema, or eczema, is a common skin disease that can affect males and females of all ages, but often starts in childhood. Recent studies show at least 4-7% of adults and 15-25% of children to be affected, with one third of patients having severe disease. It results in very itchy, red, swollen, and cracked skin. Scratching worsens the symptoms and causes the skin to become thickened over time. Patients with atopic dermatitis have an increased risk of skin infections, and many also develop hay fever or asthma. Atopic dermatitis can cause significant distress to both patients and their families. In this study, the aim is to assess the effects of a new treatment called secukinumab in patients with atopic dermatitis. A total of 30 patients will be included in the study, which will run for a total of 52 weeks.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
CollaboratorsNovartis

Timeline

Phase 2CompletedFinished
20162017201820192020202120222023202420252026
First PostedNov 2, 2015
Enrollment StartNov 1, 2015
Primary CompletionJan 30, 2018
TodayJul 2, 2026
Enrollment to primary: 2.2 yearsPosted 10.7 years ago

Interventions

Secukinumabdrug

At Weeks 0, 1, 2, 3, 4 and every 2 weeks thereafter through and including Week 12 in phase 1 of the study.

Placebodrug

At Weeks 0, 1, 2, 3, 4 and every 2 weeks thereafter through and including Week 12 in phase 1 of the study.