CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 200 enrolled
Drug / intervention
Not specified
Likely dose
Not stated in record
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Search/NCT02598271
NCT02598271N/ACompleted

Influence of Elevated Baseline Serum Creatinine and Body Composition on Acute Kidney Injury in Cardiac Surgery - The InCreAS Trial

Medical University of Vienna·observational·Posted Nov 5, 2015·Updated Mar 14, 2023

In Brief

An observational study for Acute Kidney Injury. Completed, enrolled 200 participants across 1 site.

Detailed Summary

Acute kidney injury (AKI) is an infrequent but major and well - recognized complication of cardiac surgery. Recent studies demonstrated that even minimal increases in serum creatinine are associated with a rising risk of mortality, hospital length of stay, and cost. Furthermore a cut-off for baseline serum creatinine and its influence on mortality after cardiac surgery has been shown. In this study the investigators want to test if increased bSCr is influenced by body composition. Further the investigators want to determine if the incidence of AKI is different in patients below or above the estimated cut-off. Therefore the investigators want to perform a prospective cohort analysis and will take several other body composition and nutrition parameters to test their influence on the predictive power of bSCr. Furthermore the investigators want to evaluate several novel biomarkers for AKI on their predictive effect in cardiac surgical patients.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesAustria
Collaborators--

Timeline

N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedNov 5, 2015
Enrollment StartOct 1, 2016
Primary CompletionAug 12, 2019
Study CompletionDec 30, 2022
TodayJul 2, 2026
Enrollment to primary: 2.9 yearsPosted 10.7 years ago