At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Alternative Dosing of Exemestane in Postmenopausal Women With Stage 0-II ER-Positive Breast Cancer: A Randomized Presurgical Trial
In Brief
A Phase 2 clinical trial evaluating Exemestane, Laboratory Biomarker Analysis, and 5 other interventions for Stage 0 Breast Cancer AJCC v6 and v7 and 6 related conditions. Completed, enrolled 180 participants across 5 sites in 2 countries.
Detailed Summary
This phase IIb trial studies how well alternative dosing of exemestane before surgery works in treating in postmenopausal patients with stage 0-II estrogen positive breast cancer. Chemoprevention is the use of drugs to keep breast cancer from forming or coming back. The use of exemestane may treat early stage (stage 0-II) breast cancer. Comparing the exemestane standard dose regimen versus two alternative, less frequent dose regimens may decrease undesirable symptoms and have similar efficacy in reducing serum estradiol.
Study Details
Timeline
Interventions
Given PO
Correlative studies
Correlative studies
Given PO
Ancillary studies
Ancillary studies
Undergo surgery